GLP1 hormones play a pivotal role in the activation, cascade and balance of satiating responses supporting metabolic balance and healthy weight. Recent clinical science has shown that selected natural products and nutrients can help activate GLP1 receptors directly, with intermediate metabolite formation and or synergistic multiple receptor activation and the magnitude of an effective response will vary with each approach. Sustainability of these targeted effects is also critical to ensure the underlying systems of a GLP1 cascade of responses can be achieved and maintained. This seminar will highlight product selection criteria and provide guidelines on product forms and options to help make sure selection and use of an ingredient is optimized for best outcomes.