An alert immune system is ready to properly respond to anything that may be a  danger to your health. Our Immune Protocols highlight Metabolic Maintenance®  products most helpful in supporting a responsive immune system. 

Proper nutrition, a healthful microbiome, and a balanced inflammatory response are important contributors to this process. Our Immune Maintenance Protocol is an everyday protocol to support overall health, digestive wellbeing, and proper immune function. 

Our immune system has an immediate response to an immune challenge called the innate immune system. This includes physical barriers like skin and mucosa, reflexes like the sneeze, cells protecting themselves by releasing immune chemicals, and immune cells such as Natural  Killer Cells that can respond quickly to immune challenges. 

The other pathway of response, our adaptive immune response, takes a little more time but is more specific. It involves T and B lymphocyte cell response and, most importantly, antibody formation to the specific challenge presented. 

Nutrient insufficiencies may lead to sluggish or reduced immune response. Our Immune Maintenance Protocol includes vitamins and minerals needed to nourish the effectiveness of both vital pathways of the immune response. Probiotics aid in assimilating nutrients and promoting effective gut barrier protection.

The Big One® Plus

1 capsule daily with a meal or as directed by a healthcare professional

This daily multivitamin is a go-to source of top immune-supportive nutrients, including vitamins C, D, and zinc. Foundational amounts of antioxidants (such as vitamins A, C, E, and selenium) reduce oxidative stress by scavenging free radicals that can cause cellular damage.

  • Includes 2,000 IU of Vitamin D-3, a potent immune system modulator*
  • Includes 15mg of Zinc, supporting the balanced function of both innate and adaptive elements of the immune system*
  • Supplies needed nutrients for healthy immune function in a convenient one-a-day dose

BioMaintenance® Shelf Stable Probiotic

1 capsule per day with a meal or as directed by a healthcare professional

Probiotics encourage optimal GI well-being, supporting balanced immune function. A high potency blend of 12 strains offers diversity and beneficial bacteria in the digestive tract which interact and communicate with immune cells, intestinal cells, and neurons in the body to influence digestive health, immune health, and overall well-being. 

  • Supports a balanced immune response*
  • Positively shifts microbial immune balance in the gut*
  • Offers support during times of travel, medication use, or stress*

Vitamin C Powder 

1 scoop per day or as directed by a healthcare professional

The need for additional vitamin C rises during periods of emotional, psychological or physiological stress (such as illness or infection) The functions of vitamin C in the human body are remarkably diverse, from anti-inflammatory properties to immune system support and more. 

  • Acts as an antioxidant*
  • Nourishes the adrenal glands and helps with stress response*
  • Supports normal immune function*
  • Product offered additionally in capsule form

Lifestyle tip: sleep maintenance 

No matter how well you may manage your daily health routine, there is no substitute for poor quality or lack of sleep. Cytokines, our immune system mediators, are  produced and released during sleep. Establishing a sleep hygiene routine should be a  part of your immune maintenance protocol. This includes setting and staying within a  sleep/wake schedule, reducing exposure to blue light in the evenings, and setting the  bedroom at a cooler temperature. 


The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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